Is low grade chronic inflammation a key driver of your health symptoms?
- melissarivard
- 6 days ago
- 4 min read
Updated: 5 days ago

Chronic, low-grade inflammation is like a slow-burning fire in the body; it’s not always dramatic, but over time it can significantly contribute to fatigue, hormone imbalances, autoimmune conditions, gut dysfunction, skin issues, anxiety and even burnout.
In my practice, I look for the underlying drivers of a health concern - and inflammation is often a significant contributing factor.
Here's how I assess whether chronic inflammation is playing a role in your symptoms....
Physical Signs I Look For
Low-grade inflammation often shows up in the body both in subtle and not-so-subtle ways - sometimes before it’s ever reflected in standard blood tests. During our consults, I look at the whole picture, including:
Mood + Mind:
Brain fog, sluggish thinking
Anxiety or “wired but tired” feeling
Low mood or irritability
Poor sleep
Skin:
Eczema, acne, or rosacea
Dryness, puffiness, dullness
Slow wound healing
Digestion:
Bloating or irregular bowel habits
Food sensitivities or discomfort after eating
A history of gut infections, SIBO, or IBS
Poor immune function
Food intolerances
Immune System:
Frequent infections or slow recovery
Reactivity to foods or chemicals
Diagnosed autoimmune conditions
Muscles + Joints:
Aches and pains not linked to injury
Muscle soreness that lingers
Joint stiffness, especially in the morning
Hormone Balance:
Period pain, PMS, or heavy bleeding
Cyclical acne or mood swings
Irregular or changing cycles
Signs of oestrogen dominance or progesterone insufficiency
Blood Tests I Use to Assess Inflammation
While symptoms tell part of the story, I also use functional pathology to uncover what’s going on beneath the surface. Here are some of the key bio-markers I review:
High-Sensitivity CRP (hs-CRP)
A marker of systemic inflammation, even small elevations can suggest chronic inflammatory activity.
Full Blood Count (CBC)
White blood cell patterns, haemoglobin levels, and platelet count can point to hidden infections, inflammation, or nutrient depletion.
Nutrient Markers
Iron studies: Inflammation can lower iron by trapping it in storage (functional deficiency).
B12, Folate, Vitamin D: Deficiencies can both cause and result from inflammation.
Liver Enzymes (ALT, AST, GGT)
These give insight into detoxification capacity and inflammatory load, especially if your liver is working overtime.
Metabolic Markers
Fasting glucose and insulin
HbA1c
Lipid panel (with triglycerides/HDL ratio)Inflammation can interfere with blood sugar regulation and lipid metabolism, setting the stage for metabolic imbalance.
Hormones
Cortisol (via saliva or blood): Chronic stress drives inflammation through the HPA axis.
Thyroid markers (TSH, Free T3/T4, antibodies): Inflammation often underlies sluggish thyroid function, even with “normal” labs.
Reproductive hormone tests (e.g. LH, FSH, oestradiol, progesterone, SHBG, free and total testosterone, prolactin)
Autoimmune Markers
ANA, ESR, and specific antibodies depending on presentation (e.g., anti-TPO for thyroid autoimmunity)
Lifestyle & Nutrition Clues: What Your Habits Reveal
Blood tests and physical symptoms are just part of the story. Often, chronic inflammation is being fed daily; by stress, diet, or environmental exposures—without you even realising it.
When I take a case, I ask questions designed to uncover the subtle contributors to systemic inflammation:
Daily Habits I Examine:
Sleep quality and circadian rhythm: Poor sleep is a major driver of inflammation.
Stress load + recovery: Chronic stress keeps cortisol elevated, impairing immune regulation.
Movement patterns: Both too little and too much exercise can be inflammatory.
Environmental toxins: Ongoing exposure to mould, chemicals, alcohol, smoking, or vaping increases your inflammatory burden.
Nutritional Patterns I Look For:
Ultra-processed-hyper palatable foods: These can trigger or sustain a low-grade immune response.
Food intolerances or sensitivities: Even “healthy” foods can be inflammatory if your gut barrier is compromised.
Low antioxidant and phytonutrient intake: If you're not eating the rainbow, you're not buffering oxidative stress.
Blood sugar swings: Frequent snacking or carbohydrate-heavy meals can drive insulin resistance and inflammation.
Digestive resilience: I assess not just what you eat, but how well you digest and absorb it, because inflammation often starts in the gut.
These patterns often validate what we see in pathology, and they give us actionable steps to start shifting inflammation.
Why a Holistic Interpretation Matters
Too often, blood tests are reviewed in isolation, or worse, only flagged if they're outside the "normal" reference range. But within holistic care, we look for patterns, not just outliers. We look at ALL pieces of the puzzle to make sense of the whole - In this work, context is everything.
Chronic inflammation can be a common driver of many health concerns but it’s not invisible when you know where to look for it. My clinical approach combines careful listening, symptom mapping, and thorough testing to uncover the full picture. Once we understand what’s driving the inflammation, we can start to reduce it, through nutrition, lifestyle practices, and targeted supplementation where warranted.
If you’re ready to uncover what’s really driving your symptoms - and want a clear, personalised plan to support your health from the root up - I'd love to chat..
Book a free Vitality Strategy Call to explore whether inflammation is playing a role in your health concerns and how I can support you.
You can also stay connected and receive regular holistic health insights by subscribing to my newsletter—it’s where I share practical tools, latest research, and the behind-the-scenes wisdom from my clinical practice.
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